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More on Xiaflex and Dupuytren’s Contracture

Here is another example of Xialex, the new non-surgical way to treat Dupuytren’s contracture. I will be collecting my results in this blog so people can see for themselves. This is an impressive drug folks, and obviates the need for expensive surgery and a long and painful rehab. I wa a doubter, but now, as The Monkees sing, ‘I’m a Believer!”

Here is the initial photo of the hand:

This is post injection of Xiaflex. The hand gets black & blue, but was not excessively painful. The patient did report if was sore but tolerable. I encouraged the use of ice continuously the first few days.

As you can see 3 fingers are involved–the ring, long, and small. Note: I had previously operated  on the small finger, and it was a long and painful rehab, which resulted, as you can see, in recurrence.

Now, here is the post of photo:


And here is the kicker:


This is a video after manipulation. Even I was impressed.

So, as you can clearly see,  this patient had severe Dupuytren’s contracture in 3 fingers (ring, long, and small). I used Xialex in the major cords, and needle aponeurectomy in the minor cords to get this excellent inital result. The small finger (as I noted)  was done in the traditional open surgery, which was painful and took an long time to rehabilitate. Xiaflex is a total game changer.

Here is one of the first ones I did.

Currently, she is doing well with no problems. Never went to PT/OT

Of note, one week out, the patient is stable and is very pleased with the results.

I will keep you posted in the future. Feel free to contact me for an appointment, or ask any questions.



6 Responses to More on Xiaflex and Dupuytren’s Contracture

  1. I recently came to your excellent blog through the great Tom Naughton. This post was a revelation for me. I had no idea there was a name for the weird curling I have with the small finger of my left hand. The curling is severe and I would like to at least look into getting this treatment. There is one small problem though, I’m an American living full time in Thailand. In your opinion (if you have one) could I get this treatment properly done here? Any feedback will be appreciated.


    • I am not sure. You would have to check. I would think that in some of the bigger university/state hospital that they would have the treatment, and be able to provide it to you appropriately. Thanks for reading and listening!

    • If you do happen to hear of anyone in Thaila nd carrying out this proceudre I would also appreciate knowing about them. Having very severe contractures in both hands and having undergone the trials of Xiaflex in Australia I can vouch for its effectiveness but it is yet to be cleared by the TGA for use here. Hence Thailand would be a good close option. Hope to hear more about your successes with this stuff. Cheers.

      • I live in one of the southern provinces and I have not been able to find anyone down here familiar with this procedure. I’ve been told to try at the international hospitals up in Bangkok. I will be up there in February. If I have any luck I will let you know.

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